The highly stereoselective formation of pipecolic acid N-oxide and related derivatives

✍ Scribed by Ian A. O'Neil; Andrew J. Potter

• Publisher: Elsevier Science
• Year: 1997
• Tongue: French
• Weight: 164 KB
• Volume: 38
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(97)01258-6

✦ Synopsis

N-Alkylated derivatives of pipecolic acid are shown to undergo highly stereoselective oxidation to give stable tertiary amine N-oxides. The ester derivatives show a high degree of stability compared to their proline analogues.