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The Heterochromatin Protein 1 Prevents Telomere Fusions in Drosophila

โœ Scribed by Laura Fanti; Giovanna Giovinazzo; Maria Berloco; Sergio Pimpinelli


Book ID
117736124
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
332 KB
Volume
2
Category
Article
ISSN
1097-2765

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Heterochromatin normally has prescribed chromosomal positions and must not encroach on adjacent regions. We demonstrate that the fission yeast protein Epe1 stabilises silent chromatin, preventing the oscillation of heterochromatin domains. Epe1 loss leads to two contrasting phenotypes: alleviation o