𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The Herbarium of Ferrante Imperato at Naples

✍ Scribed by GIGLIOLI, ITALO

Book ID
109439134
Publisher
Nature Publishing Group
Year
1903
Tongue
English
Weight
239 KB
Volume
67
Category
Article
ISSN
0028-0836

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K-ras mutation in the tumour of King Fer
K-ras mutation in the tumour of King Ferrante I of Aragon (1431–1494) and environmental mutagens at the Aragonese court of Naples
✍ Gino Fornaciari; Antonio Marchetti; Silvia Pellegrini; Rosalba Ciranni πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 404 KB

The autopsy of the mummy of Ferrante I of Aragon, King of Naples (1431 -1494) revealed an adenocarcinoma extensively infiltrating the muscles of the small pelvis. A molecular study of neoplastic tissue observed a typical mutation of the K-ras gene codon 12: the normal sequence GGT (glycine) was alte