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The HER-2-Targeting Antibodies Trastuzumab and Pertuzumab Synergistically Inhibit the Survival of Breast Cancer Cells

✍ Scribed by Nahta, R.

Book ID
118117238
Publisher
American Association for Cancer Research
Year
2004
Tongue
English
Weight
262 KB
Volume
64
Category
Article
ISSN
0008-5472

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Human epidermal growth factor receptor 2 (HER2) is frequently overexpressed in human breast cancers. It is known to drive tumor growth and progression and represents a prominent target in breast cancer therapy. The endothelin (ET) system, in particular ET-1 and its receptor ET A R, is of major relev