𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The hazards of cadmium in man and animals

✍ Scribed by Hans Winter


Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
875 KB
Volume
2
Category
Article
ISSN
0260-437X

No coin nor oath required. For personal study only.

✦ Synopsis


Abstract

The health hazards of cadmium have attracted increased attention since the rock‐soil‐plant‐animal‐man relationship became better known, and when it was realized that low doses are cumulative over a very long time and that increasing industrial pollution may endanger the general population. Major sources are mining and smelting, metal coating, welding, incineration of refuse, fossil fuels and use of sewage sludge as fertilizer. Intoxication usually results from ingestion or inhalation, but the pathogenesis is not well understood. With chronic intoxication, the critical organ is the kidney, where one third of the body cadmium may accumulate. Apart from diseases so far recognized in man, a large number of pathological conditions have been produced in experimental animals, including congenital abnormalities, ovarian, testicular and brain lesions, as well as interference with the immune system. Their full significance for man is not yet known. Cadmium plays no useful role in the organism and its intake should be limited as much as possible, although being ubiquitous it cannot be completely eliminated. Legislation for maximum permissible levels in different food items was attempted, but is not workable and is not in the best interest of the consumer. Instead, the whole food basket of the consumer should be monitored to limit weekly intake to prescribed levels. In addition, hygienic measures should be encouraged, including cleaning, peeling or blanching of fruit and vegetables, removal of outer leaves of cabbage and lettuce to eliminate the effects of aerial pollution, discretion in using sewage sludge as fertilizer, washing hands and possibly avoiding excessive consumption of kidneys and livers.


πŸ“œ SIMILAR VOLUMES


Pharmacokinetics of fenclozic acid in an
✍ D. S. Platt πŸ“‚ Article πŸ“… 1971 πŸ› John Wiley and Sons 🌐 English βš– 734 KB

The pharmacokinetic properties of the anti-inflammatory agent, fenclozic acid, have been established in the dog, calf, sheep, and horse after intravenous administration and also in the rat, mouse, guinea pig, monkey, and man after oral dosage. At doses equivalent to those therapeutically effective i

Propoxyphene: Pathways of metabolism in
✍ Susan L. Due; Hugh R. Sullivan; Robert E. McMahon πŸ“‚ Article πŸ“… 1976 πŸ› John Wiley and Sons 🌐 English βš– 711 KB

Through the combined use of stable isotope labeling and gas chromatographic mass spectrometric analysis, the metabolic patterns for propoxyphene have been determined in laboratory animals and man. The rat and dog eliminated propoxyphene and its metabolites principally via the bile, while the rabbit

Anatomy, Visualization and Sampling of t
✍ Steven M. Strasberg; P. Robert C. Harvey; Steven Gallinger πŸ“‚ Article πŸ“… 1984 πŸ› John Wiley and Sons 🌐 English βš– 410 KB

Difficulties in obtaining proper bile samples are due to inaccessibility of the biliary tree and to distortions induced by sampling methods. One must be cognizant of the effects of diet on bile secretion and gallbladder motility. Experimental methods which interrupt the enterohepatic circulation or