๐”– Bobbio Scriptorium
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The hazard of acute radiation pneumonitis in children receiving mediastinal radiation

โœ Scribed by Philip Littman; Lawrence W. Davis; Jerry Nash; Melvin Tefft; Patricia Borns; Philip Lepanto

Publisher
John Wiley and Sons
Year
1974
Tongue
English
Weight
693 KB
Volume
33
Category
Article
ISSN
0008-543X

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โœฆ Synopsis

T w o children are described who developed fatal pneumonitis after receiving what is considered to be an acceptable dose of irradiation to the whole thorax, plus additional radiotherapy to the mediastinum. T h e authors conclude that irradiation to the whole thorax with addition of further radiotherapy to the mediastinum is likely to cause severe acute radiation pneumonitis. T h e use of concomitant chemotherapy may accentuate the hazard.

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ZO patients with bulky mediastinal Hodgkin's Disease (maximum mediastinal width divided by the maximum intrathoracic diameter for a mediastinal mass ratio (MMR) > 0.33 were treated at Stanford University with definitive radiation therapy alone. The majority of these patients were selected to receive