The Hairpin Ribozyme
β Scribed by Arnold Hampel; Steven Nesbitt; Richard Tritz; Mitchell Altschuler
- Book ID
- 115638518
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 435 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1046-2023
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The hairpin ribozyme is a naturally occurring RNA that catalyzes sequenceβspecific cleavage and ligation of RNA. It has been the subject of extensive biochemical and structural studies, perhaps the most detailed for any catalytic RNA to date. Comparison of the structures of its constitu
Recent studies of the hairpin ribozyme have revealed a distinct catalytic mechanism for this small RNA motif. Inner-sphere coordinated metal ions are not required, as the inert metal ion complex cobalt hexammine promotes catalysis. Detailed kinetic analyses have defined rates of individual steps in