THE GROWTH HORMONE INDEPENDENT INSULIN-LIKE GROWTH FACTOR-I BINDING PROTEIN BP-28 IS ASSOCIATED WITH SERUM INSULIN-LIKE GROWTH FACTOR-I INHIBITORY BIOACTIVITY IN ADOLESCENT INSULIN-DEPENDENT DIABETICS
โ Scribed by A. M. TAYLOR; D. B. DUNGER; M. A. PREECE; J. M. P HOLLY; C. P. SMITH; J. A. H. WASS; S. PATEL; V. E. TATE
- Book ID
- 114719105
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 725 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0300-0664
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๐ SIMILAR VOLUMES
Serum levels of insulin-like growth factor I are reduced in patients with Type 1 (insulin-dependent) diabetes mellitus. To evaluate the role of the hepatic growth hormone receptor in the decreased serum concentrations of insulinlike growth factor I, serum levels of the high affinity growth hormone-b
Multiple factors contribute to the growth retardation which is a characteristic feature of uncontrolled diabetes. In this report we have examined the effects of streptozotocin-induced (STZ) diabetes on expression of insulin-like growth factor-I (IGF-I) and insulin-like growth factor binding protein-