The Greig cephalopolysyndactyly syndrome: Report of a family and review of the literature
β Scribed by Gollop, Thomaz Rafael ;Fontes, Luiz Roberto ;Opitz, John M. ;Reynolds, James F.
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 607 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0148-7299
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## Abstract Greig cephalopolysyndactyly syndrome (GCPS) is a rare multiple congenital anomaly syndrome that is inherited in an autosomal dominant pattern and is caused by haploinsufficiency of the __GLI3__ gene. The syndrome typically includes preaxial or mixed preβ and postaxial polydactyly and cu
We report on the first known Bedouin family with Greig cephalopolysyndactyly syndrome (MIM 175700). The index patient and his father shared pre-and postaxial polysyndactyly, mild mental retardation, and corpus callosum dysgenesis. Their phenotypic findings were compared with reported cases of both G
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