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The gonads of human true hermaphrodites

✍ Scribed by Willem A. Niekerk; Andries E. Retief

Publisher
Springer
Year
1981
Tongue
English
Weight
635 KB
Volume
58
Category
Article
ISSN
0340-6717

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A search for Y-specific DNA sequences has been performed in a sample of seven 46,XX true hermaphrodites and one 45,X mixed gonadal dysgenesis case and compared with a sample of 11 XX males. Using six Y-specific DNA probes no hybridization signal was obtained in the hermaphrodite group; in contrast,

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We have studied nine patients aged 1 month to 16 years with 46, XX karyotypes and testicular tissue. Some of these patients were followed through puberty. Phenotypically, two presented normal and seven abnormal external genitalia (AG). Among this latter group, four showed hypospadias and three true