The GNAS1 T393C Polymorphism Predicts Survival in Patients With Advanced Squamous Cell Carcinoma of the Larynx
โ Scribed by Goetz F. Lehnerdt; Peter Franz; Sebastian Winterhoff; Agnes Bankfalvi; Sara Grehl; Stephan Lang; Kurt W. Schmid; Winfried Siffert; Klaus Jahnke; Ulrich H. Frey
- Book ID
- 110089426
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 214 KB
- Volume
- 118
- Category
- Article
- ISSN
- 0023-852X
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Tumor suppressor genes play an important role in normal growth regulation. Loss or inactivation of these genes has been implicated in the development of squamous cell cancer and progression of neoplasia. Previous studies in our laboratories have implicated chromosome 18 long-arm deletions as a possi
## Abstract ## Background We compared postoperative complications and oncologic results after laryngectomy of patients with laryngeal squamous cell carcinoma (SCC), with and without airway obstruction. ## Methods We retrospectively reviewed the medical records of 544 patients with laryngeal SCC