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The Glutathione Redox Couple Modulates Zinc Transfer from Metallothionein to Zinc-Depleted Sorbitol Dehydrogenase

โœ Scribed by Li-Juan Jiang, Wolfgang Maret and Bert L. Vallee


Book ID
123641176
Publisher
National Academy of Sciences
Year
1998
Tongue
English
Weight
1002 KB
Volume
95
Category
Article
ISSN
0027-8424

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## Abstract Glutathione (GSH), in addition to serving as a redox buffer in cellular environment, has been suggested as a modulator in metal regulation and homeostasis by metallothioneins (MTs). The interactions of MTs with both GSH and its oxidized form GSSG have been shown to govern the direction