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The glutathione-linked metabolism of 2-allyl-2-isopropy-lacetamide in rats. Further evidence for the formation of a reactive metabolite

โœ Scribed by Philippa M. Edwards; Jean E. Francis; Francesco De Matteis


Book ID
113135850
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
502 KB
Volume
23
Category
Article
ISSN
0009-2797

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โœ Ronald Breslow; Pyare Lal Khanna ๐Ÿ“‚ Article ๐Ÿ“… 1977 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 187 KB

We have described the reaction of 1-chloro-[2.2.0]bicyclohexa-2,5-diene (I) with lithium dialkylamides to afford dialkylanilines. 1 The critical finding with regard to the mechanism of this change is that the reaction of I with lithium dimethylamide in Me2ND in the presence of diphenylisobenzofuran