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The glucokinase gene promoter polymorphism − 30G>A (rs1799884) is associated with fasting glucose in healthy pregnant women but not with gestational diabetes

✍ Scribed by Izabella C.R. Santos; Henrique R. Frigeri; Rosângela R. Réa; Ana Cristina R. Almeida; Emanuel M. Souza; Fábio O. Pedrosa; Cyntia M.T. Fadel-Picheth; Geraldo Picheth

Book ID: 116348673
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 77 KB
Volume: 411
Category: Article
ISSN: 0009-8981
DOI: 10.1016/j.cca.2010.03.011

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A commonly occurring sequence variant in the islet-specific promoter of the glucokinase gene (-30 G to A) has been variably reported to be associated with reduced insulin secretory responses to oral glucose. The effect of this promoter variant may be subtle and only become apparent under conditions

The glucokinase gene promoter polymorphism −&#xa0;30G>A (rs1799884) is associated with fasting glucose in healthy pregnant women but not with gestational diabetes

The glucokinase gene promoter polymorphism − 30G>A (rs1799884) is associated with fasting glucose in healthy pregnant women but not with gestational diabetes