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The genome-wide landscape of copy number variations in the MUSGEN study provides evidence for a founder effect in the isolated Finnish population

✍ Scribed by Kanduri, Chakravarthi; Ukkola-Vuoti, Liisa; Oikkonen, Jaana; Buck, Gemma; Blancher, Christine; Raijas, Pirre; Karma, Kai; Lähdesmäki, Harri; Järvelä, Irma

Book ID: 120218853
Publisher: Nature Publishing Group
Year: 2013
Tongue: English
Weight: 293 KB
Volume: 21
Category: Article
ISSN: 1018-4813
DOI: 10.1038/ejhg.2013.60

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## Abstract We propose a new approach for the analysis of copy number variants (CNVs)for genome‐wide association studies in family‐based designs. Our new overall association test combines the between‐family component and the within‐family component of the family‐based data so that the new test stat