Differential activities of E2F family me
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Angela M. Pierce; Robin Schneider-Broussard; Jennifer L. Philhower; David G. Joh
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Article
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1998
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John Wiley and Sons
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English
β 196 KB
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Several regulators of E2F transcriptional activity, including the retinoblastoma tumor suppressor (Rb) protein, p16 Ink4a , cyclin D1, and cyclin-dependent kinase 4, have been shown to be targets for genetic alterations that underlie the development of human cancers. Deregulation of E2F transcriptio