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The genetics of Parkinson's disease

✍ Scribed by HA Rohan de Silva; Naheed L Khan; Nicholas W Wood


Book ID
117654664
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
117 KB
Volume
10
Category
Article
ISSN
0959-437X

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Over the last few years, several genes for monogenic forms of Parkinson's disease (PD) have been mapped and/or cloned. Mutations have been identified in the gene for alpha-synuclein in rare families with dominant PD, indicating that aggregation of this protein in Lewy bodies is probably a crucial st