Molecular genetics of metachromatic leuk
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Volkmar Gieselmann; Joel Zlotogora; Ann Harris; David A. Wenger; C. Phillip Morr
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Article
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1994
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John Wiley and Sons
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English
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Metachromatic leukodystrophy is an autosomal recessive inherited lysosomal storage disease. It can be caused by mutations in two different genes, the arylsulfatase A and the prosaposin gene. These genes encode two proteins that are needed for the proper degradation of cerebroside sulfate, a glycolip