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The Genes Induced by Signal Transducer and Activators of Transcription (STAT)3 and STAT5 in Mammary Epithelial Cells Define the Roles of these STATs in Mammary Development

✍ Scribed by Clarkson, Richard W. E.; Boland, Marion P.; Kritikou, Ekaterini A.; Lee, Jennifer M.; Freeman, Tom C.; Tiffen, Paul G.; Watson, Christine J.


Book ID
127361190
Publisher
Endocrine Society
Year
2006
Tongue
English
Weight
645 KB
Volume
20
Category
Article
ISSN
0888-8809

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The STAT proteins (signal transducers and activators of transcription) are transcription factors mediating cytokine/growth factor signaling, which play important role in controlling cell cycle progression and apoptosis. In many cancer cell lines and tumors (including gliomas) the STAT proteins (in p