✦ LIBER ✦

The genes for growth hormone and chorionic somatomammotropin are on the long arm of human chromosome 17 in region q21→qter

✍ Scribed by Donna L. George; John A. Phillips; Uta Francke; Peter H. Seeburg

Publisher: Springer
Year: 1981
Tongue: English
Weight: 495 KB
Volume: 57
Category: Article
ISSN: 0340-6717
DOI: 10.1007/bf00282009

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✦ Synopsis

We used a cloned cDNA probe for human growth hormone and Southern blotting techniques to analyze DNA from a series of rodent x human somatic cell hybrids for the presence of growth hormone-related sequences. Our results provide evidence for the assignment of the genes for growth hormone and chorionic somatomammotropin as well as a growth hormone-like gene to human chromosome 17. Analysis of mouse x human hybrid cells containing only part of the long arm of chromosome 17 enabled us to localize these genes to region 17q21 to 17qter.