The Generation of Immunocompetent Dendritic Cells From CD34+ Acute Myeloid or Lymphoid Leukemia Cells
β Scribed by Takahide Tsuchiya; Masao Hagihara; Yasuhito Shimakura; Yoko Ueda; Balgansuren Gansuvd; Batmunkh Munkhbat; Hiroyasu Inoue; Kei Tazume; Shunichi Kato; Tomomitsu Hotta
- Publisher
- Carden Jennings Publishing
- Year
- 2002
- Tongue
- English
- Weight
- 501 KB
- Volume
- 75
- Category
- Article
- ISSN
- 0925-5710
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π SIMILAR VOLUMES
## Abstract Leukemic dendritic cells (DCs) that are derived from acute myeloid leukemia (AML) cells display lowβlevel expression of several key molecules. We investigated the optimal combination of cytokines needed to generate potent leukemic DCs from AML cells __in vitro__. AML cells were cultured
Clinical application of immunotherapy for acute myeloid leukemia (AML) requires the efficient induction of dendritic cells (DCs) from AML blast cells using in vitro culture. We examined the effect of autologous serum on the properties of leukemic DCs derived from leukemic cells of AML patients by cu