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The Generation of Antimicrobial Peptide Activity: A Trade-off between Charge and Aggregation?

✍ Scribed by Dr. Marc Torrent; Javier Valle; Prof. M. Victòria Nogués; Dr. Ester Boix; Prof. David Andreu

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
637 KB
Volume
50
Category
Article
ISSN
0044-8249

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## Abstract In our previous study, we utilized a 26‐residue amphipathic α‐helical antimicrobial peptide L‐V13K (Chen et al., Antimicrob Agents Chemother 2007, 51, 1398–1406) as the framework to study the effects of peptide hydrophobicity on the mechanism of its antimicrobial action. In this study,