## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
The generation and cyclisation of pyridinium radicals as a potential route to indolizidine alkaloids
β Scribed by Adrian P. Dobbs; Keith Jones; Ken T. Veal
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 235 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
The cyclisation of pyridine radicals derived from 2-bromo-N-alkyl pyridinium salts is described. The subsequent hydrogenation of the pyridinium salts is shown to give both the indolizidine and quinolizidine skeletons.
π SIMILAR VOLUMES
## A potentialb general route to the I-asabi~clo[n.m.O]alkune skeleton of various alkaloids is embodied in the intramolecular 1 J-&polar cycknuidition of aliphatic askies with axhloroalkenes. Cycloaddition is followed &Y rearrangement and intramolecular N-alkytation, @or&ng bicyctic iminium ions 1 i
Allyl trifluoroethyl ethers 2a-2d were prepared; each underwent efficient dehydrofluorination/metallation and trapping to afford a range of difluoroenol silanes and stannanes which rearranged easily and efficiently to the acyl metals. Fluoride-mediated benzylation and allylation of an acylsilane, an