Combined sialyltransferase (ST) activities were induced in the HN9 hippocampal cell line following treatment with the synthetic glucocorticoid dexamethasone (dex) for 24 hr. Induction occurred in a dosedependent manner, with the maximum induction of a 2-fold increase over control enzyme levels occur
The generation and characterization of a rat neural cell line overexpressing the α2,6(N) sialyltransferase
✍ Scribed by Kieran C Breen; Astrid Potratz; Niki Georgopoulou; Konrad Sandhoff
- Book ID
- 110244864
- Publisher
- Springer US
- Year
- 1998
- Tongue
- English
- Weight
- 578 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1573-4986
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The function of the neural cell adhesion molecule, NCAM, is modulated by the expression of the Nlinked polysialic acid (PSA) oligosaccharide chain, with PSA serving to decrease the adhesive potential of the protein backbone. In this study, we have generated clonal cells of the rat B104 and human SH-
5'-Nucleotidase has been purified from rat glioblastoma cells (Rugli cells). The enzyme has been solubilized from plasma membranes by using Triton X-100 and CHAPS. Two affinity chromatographies on concanavalin A and 5'-AMP-Sepharose render the purified enzyme with a high specific activity (76.36 mum
We compared several sialyltransferase activities related to synthesis of O-linked and N-linked sialylglycoproteins in Ehrlich ascites tumor cells that grow normally in murine ascites, but are not adherent nor grow in tissue culture (na-EAT cells), with those in cells that were selected to grow in ti