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The gene for proliferating cell nuclear antigen (Pcna) maps to mouse Chromosome 2

✍ Scribed by Cathy Abbott; Alison Pilz; Heather Moseley; Jo Peters

Publisher
Springer-Verlag
Year
1992
Tongue
English
Weight
436 KB
Volume
3
Category
Article
ISSN
0938-8990

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✦ Synopsis

The structural gene for proliferating cell nuclear antigen (Pcna) has been mapped to mouse Chromosome (Chr) 2 by use of a PCR-based assay. With somatic cell hybrids, Pcna was mapped between the T(2;4)13H and T(2;4)1Sn breakpoints. An interspecific backcross was employed to map Pcna 1.9 +/- 1.3 cM distal to Il-lb. This was confirmed by mapping Pcna in the BXH recombinant inbred (RI) strains; no recombinants were seen between Il-la and Pcna. In addition, a PCNA-related sequence (Pcna-rsl) was mapped to Chr 19 in the BXH RI strains.

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