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The Gene Expression of Coagulation Factor VIII in Mammalian Cell Lines

✍ Scribed by Chun Chen; Xiang-Dong Fang; Jiang Zhu; Xiang-Fu Wu; Zu-Chuan Zhang; Jian-Xin Gu; Zhen-Yi Wang; Cheng-Wu Chi


Book ID
117259041
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
328 KB
Volume
95
Category
Article
ISSN
0049-3848

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The gene expression of heme oxygenase-1 (HO-1) was studied in mammalian cell lines exposed to hyperoxia. Northern blot analysis demonstrated that hyperoxic exposure increased the HO-1 mRNA levels in various types of cells, including human hepatoma (HepG2) cells. This increase was time-and dose-depen