The gene encoding the equine soluble class I molecule is linked to the horse MHC
✍ Scribed by Andrew M. Lew; Ernest Bailey; Robert B. Valas; John Coligan
- Publisher
- Springer-Verlag
- Year
- 1986
- Tongue
- English
- Weight
- 331 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0093-7711
No coin nor oath required. For personal study only.
✦ Synopsis
An equine soluble class I molecule (ESCI) analogous to the Q10 molecule of the mouse has been described by Lew and co-workers (1986a). The QIO gene is located in the Qa region (Weiss et al. 1984), which is immediately telomeric to the H-2 region of the mouse. By analogy to the lymphocyte antigen systems of other species, e. g., HLA and H-2, the equine lymphocyte antigen (ELA) system of the horse appears to be encoded by the major histocompatibility complex (MHC) of the horse (Bailey 1980, Lazary et al. 1981, Antczak et al. 1982). In the context of four international workshops on ELA, a single locus designated ELA-A was