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The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

✍ Scribed by Schmitz, Gerd; Bodzioch, Marek; Orsó, Evelyn; Klucken, Jochen; Langmann, Thomas; Böttcher, Alfred; Diederich, Wendy; Drobnik, Wolfgang; Barlage, Stefan; Büchler, Christa; Porsch-Özcürümez, Mustafa; Kaminski, Wolfgang E.; Hahmann, Harry W.; Oette, Kurt; Rothe, Gregor; Aslanidis, Charalampos; Lackner, Karl J.


Book ID
109486156
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
507 KB
Volume
22
Category
Article
ISSN
1061-4036

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The Tangier disease gene encodes yet ano
✍ Attilio Rigotti; David E. Cohen 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 42 KB

## Genes have a major role in the control of high-density lipoprotein (HDL) cholesterol (HDL-C) levels. Here we have identified two Tangier disease (TD) families, confirmed 9q31 linkage and refined the disease locus to a limited genomic region containing the gene encoding the ATP-binding cassette