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The Gating Mechanism of a P2X4 Receptor: Normal Mode Analysis and Molecular Dynamics Simulations

✍ Scribed by Du, Juan; Dong, Hao; Xiang Zhou, Huan

Book ID
122264252
Publisher
Biophysical Society
Year
2012
Tongue
English
Weight
57 KB
Volume
102
Category
Article
ISSN
0006-3495

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## Abstract __An unambiguous understanding of the binding mode of human progesterone to its receptor still eludes experimental search. According to the X‐ray structure of the ligand‐binding domain, only one (O3) of the two keto groups at the ligand ends (O3 and O20) should play a role. This result