✦ LIBER ✦
The gatekeeper mutation T315I confers resistance against small molecules by increasing or restoring the ABL-kinase activity accompanied by aberrant transphosphorylation of endogenous BCR, even in loss-of-function mutants of BCR/ABL
✍ Scribed by Mian, A A; Schüll, M; Zhao, Z; Oancea, C; Hundertmark, A; Beissert, T; Ottmann, O G; Ruthardt, M
- Book ID
- 109887101
- Publisher
- Nature Publishing Group
- Year
- 2009
- Tongue
- English
- Weight
- 465 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0887-6924
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