The Gap Junctional Protein Connexin(Cx)43 in Testicular Cancer: its Loss Marks Progession from Carcinoma In Situ to Invasive Germ Cell Tumour

Cell cycle regulators in testicular canc

Cell cycle regulators in testicular cancer: Loss of p18INK4C marks progression from carcinoma in situ to invasive germ cell tumours

✍ Jirina Bartkova; Minna Thullberg; Ewa Rajpert-De Meyts; Niels E. Skakkebaek; Jir 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 French ⚖ 202 KB 👁 2 views

Cell cycle regulators govern cellular proliferation, modulate differentiation and, when defective, contribute to oncogenesis. Here, we examined expression of cyclins A, B1 and E, and cyclin-dependent kinase (CDK) inhibitors p18 INK4C (p18), p21 WAF1/Cip1 (p21) and p27 Kip1 (p27), in normal human adu