The G protein-coupled receptor-associated protein 1 (GASP-1) regulates rimonabant-induced downregulation of GPR55
β Scribed by Julia Kargl; Nariman A Balenga; Jennifer L Whistler; Maria Waldhoer
- Publisher
- BioMed Central
- Year
- 2011
- Tongue
- English
- Weight
- 64 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1471-2210
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β¦ Synopsis
Kargl et al.:
The G protein-coupled receptorassociated protein 1 (GASP-1) regulates rimonabant-induced downregulation of GPR55. BMC Pharmacology 2011 11(Suppl 2):A57.
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Kargl et al.: The trafficking of GPR55 is regulated by the G protein-coupled receptor-associated sorting protein 1. BMC Pharmacology 2010 10(Suppl 1):A1.
G-protein-coupled receptors (GPCRs) are integral membrane proteins involved in signal transduction and constitute major drug targets for disease therapy. Aptamers, which are globular RNA or DNA molecules evolved to specifically bind a target, could represent a valuable tool with which to probe the r
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