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The functional efficiency of lipogenic and cholesterogenic gene expression in normal mice and in mice lacking the peroxisomal proliferator-activated receptor–alpha (PPAR–α)

✍ Scribed by Geoffrey F Gibbons; Dilip Patel; David Wiggins; Brian L Knight


Book ID
114098815
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
487 KB
Volume
42
Category
Article
ISSN
0065-2571

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## Abstract Peroxisome proliferator‐activated receptor alpha (PPARα) is a member of the nuclear hormone receptor superfamily that can be activated by natural fatty acids and various xenobiotics, including clofibrate. This transcription factor primarily regulates genes involved in lipid metabolism a