The functional dissection of human peripheral null cells with respect to antibody-dependent cellular cytotoxicity and natural killing

Natural killer (NK) cells as effectors o

Natural killer (NK) cells as effectors of antibody-dependent cytotoxicity with chimeric antibodies reactive with human squamous-cell carcinomas of the head and neck

✍ Myung-Whun Sung; Satoshi Yasumura; Jonas T. Johnson; Guus A. M. S. Van Dongen; T 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 939 KB

In patients with cancer, antibody-dependent cellular cytotoxicity (ADCC) may be used as a laboratory test or for enhancing immunotherapy with murine monoclonal or chimeric mouse/ human anti-tumor antibodies (mMAbs or cMAbs, respectively). We have established an ADCC assay with lgG, cMAb SF-25, using