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The function of PML in p53-dependent apoptosis

✍ Scribed by Paolo Pandolfi, Pier; Guo, Ailan; Salomoni, Paolo; Luo, Jianyuan; Shih, Alan; Zhong, Sue; Gu, Wei


Book ID
109771078
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
381 KB
Volume
2
Category
Article
ISSN
1465-7392

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## BACKGROUND. Although p53 gene mutation frequently is observed in ovarian carcinoma, the function of the p53 gene in chemosensitivity has not been defined conclusively. The objective of the current study was to elucidate the relation between chemotherapy-induced apoptosis through the p53 pathway