The Friedel-Crafts Acylation Reaction I. Substituent Effect in the Friedel-Crafts Benzoylation of Toluene
โ Scribed by P. J. Slootmaekers; R. Roosen; J. Verhulst
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2010
- Weight
- 846 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0037-9646
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Dans le cadre de l'ktude de la correlation structure-rhctivitk dans la rhction d'acylation du toluene par des chlorures d'acide, catalysQ par le chlorure d'aluminium, on a ktudi6 le comportement de divers chlorures de cinnamoyle, substituks en mkta ou en para. La rhction se prbsente comme une rhcti
## Abstract The aluminium chlorideโcatalysed reaction between benzene and methyl chloride is considered as a method for producing toluene. It is shown that, under suitably chosen conditions, toluene may become the chief product, but it is impossible to prevent the formation of higher methylated com
## Abstract Addition compounds of Lewis acids MX~__n__~ and acyl halides R๏ฃฟCOX occur as intermediates in FriedelโCrafts acylations. IR and NMR studies on these intermediates have indicated the probable existence of structural isomers. In Xโray structural analysis, it is possible to distinguish two