## Abstract ## Background Type 2 diabetes is associated with cognitive dysfunction and increases the risk of dementia in the elderly. The aim of this study was to explore, by means of magnetic resonance (MR) imaging, possible relationships among clinical profiles of diabetes, cognitive function, w
The frequency of cognitive dysfunction in elderly Sri Lankans with type 2 diabetes mellitus
β Scribed by N. Rajakumaraswamy; I. H. Rajapakse; D. J. S. Fernando
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 40 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0885-6230
- DOI
- 10.1002/gps.2022
No coin nor oath required. For personal study only.
β¦ Synopsis
Type 2 diabetes mellitus increases risks of dementia (Allen et al., 2004). This association has not been investigated in the developing world. Morbidity and mortality from complications of type 2 diabetes are high in elderly Sri Lankan patients (Fernando et al., 1992). The prevalence of dementia in a semi-urban population was 4% (De Silva et al., 2003). We studied the frequency of cognitive dysfunction among elderly Sri Lankans with type 2 diabetes by recruiting a random sample of 204 persons from a specialist diabetic clinic database. Their demographic, health and diabetes-related data were obtained from medical records on clinical database software (Electronic Medical Record, Endocrine & Metabolic Disease Trust and SS Technologies, Sri Lanka). The data not available on the database were obtained at screening during a study visit. The development of the database received ethical review committee approval for a larger study of diabetes complications and the dementia screening component of this study was the student elective project of the first author.
All participants were screened using a Sri Lankan version of Mini Mental State Examination (de Silva and Gunatilake, 2002). Those with a MMSE score of 25 or less and were examined by a psychiatrist using
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