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The frequency and distribution of sister chromatid exchanges in human chromosomes

โœ Scribed by William F. Morgan; Peter E. Crossen

Book ID
118287633
Publisher
Springer
Year
1977
Tongue
English
Weight
423 KB
Volume
38
Category
Article
ISSN
0340-6717

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Lymphocytes from 20 notmal subjects (11 male and 9 female) were examined for the frequency and location of sister chromatid exchanges (SCE) by the BrdU--Giemsa method. The mean frequency of SCE was 6.37 with little significant variation. One subject had a high number of exchanges in chromosome 1 whi

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## Abstract Peripheral lymphocytes from 3 scleroderma patients with systemic disease and from 3 normal controls were examined for frequencies of chromosomal aberration and sister chromatid exchange (SCE). Significant increases in the levels of chromosomal anomaly and SCE were found for all 3 patien