The French Series of Autosomal Dominant Early Onset Alzheimer's Disease Cases: Mutation Spectrum and Cerebrospinal Fluid Biomarkers
✍ Scribed by Wallon, David ;Rousseau, Stéphane ;Rovelet-Lecrux, Anne ;Quillard-Muraine, Muriel ;Guyant-Maréchal, Lucie ;Martinaud, Olivier ;Pariente, Jérémie ;Puel, Michèle ;Rollin-Sillaire, Adeline ;Pasquier, Florence ;Le Ber, Isabelle ;Sarazin, Marie ;Croisile, Bernard ;Boutoleau-Bretonnière, Claire ;Thomas-Antérion, Catherine ;Paquet, Claire ;Moreaud, Olivier ;Gabelle, Audrey ;Sellal, François ;Sauvée, Mathilde ;Laquerrière, Annie ;Duyckaerts, Charles ;Delisle, Marie-Bernadette ;Streichenberger, Nathalie ;Lannes, Béatrice ;Frebourg, Thierry ;Hannequin, Didier ;Campion, Dominique ;,
- Book ID
- 127230990
- Publisher
- IOS Press
- Year
- 2012
- Tongue
- English
- Weight
- 92 KB
- Volume
- 30
- Category
- Article
- ISSN
- 1387-2877
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Mutations in the presenilin-1 (PS1) gene account for the majority of familial early-onset Alzheimer's disease (EOAD) cases. We screened the coding part of the PS1 gene for the presence of mutations in a French family with EOAD, using single strand conformation polymorphism (SSCP) analysis. Patients