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The fragile X protein controls microtubule-associated protein 1B translation and microtubule stability in brain neuron development

✍ Scribed by Lu, R.; Wang, H.; Liang, Z.; Ku, L.; O'Donnell, W. T.; Li, W.; Warren, S. T.; Feng, Y.

Book ID
126654165
Publisher
National Academy of Sciences
Year
2004
Tongue
English
Weight
476 KB
Volume
101
Category
Article
ISSN
0027-8424

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MAP1B is a major cytoskeletal protein in growing axons and is strongly regulated during brain development. The present studies compare the expression of MAP1B mRNA, the protein, and its phosphorylated isoform in spinal cord and dorsal root ganglia (DRGs) with brain. In spinal cord and brain, MAP1B m