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The formation of methylated bases in DNA by dimethylnitrosamine and its relation to differences in the formation of tumours in the livers of GR and C3Hf mice

✍ Scribed by L. den Engelse


Book ID
113135424
Publisher
Elsevier Science
Year
1974
Tongue
English
Weight
874 KB
Volume
8
Category
Article
ISSN
0009-2797

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## Abstract C3H/HeJ(C3H) mice are approximately 50‐fold more susceptible to liver‐tumor induction than C57BL/6J(B6) mice. This difference in susceptibility is a consequence of allelic differences in hepatocarcinogen sensitivity(__Hcs__) genes that control the growth of preneoplastic lesions in the