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The Folding Pathway of a Protein at High Resolution from Microseconds to Seconds

✍ Scribed by Bengt Nölting, Ralph Golbik, José L. Neira, Andrés S. Soler-Gonzalez, Gideon Schreiber and Alan R. Fersht

Book ID
123640415
Publisher
National Academy of Sciences
Year
1997
Tongue
English
Weight
898 KB
Volume
94
Category
Article
ISSN
0027-8424

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## Abstract __Pyrococcus furiosus__, a hyperthermophilic archaeon growing optimally at 100°C, encodes three protein chaperones, a small heat shock protein (sHsp), a prefoldin (Pfd), and a chaperonin (Cpn). In this study, we report that the passive chaperones sHsp and Pfd from __P. furiosus__ can bo