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The folding intermediate of reversibly denatured human prostatic acid phosphatase

✍ Scribed by Radoslawa Kuciel; Aleksandra Mazurkiewicz; Wlodzimierz S. Ostrowski


Book ID
116091592
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
777 KB
Volume
18
Category
Article
ISSN
0141-8130

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It has been shown that human stefin B exhibits molten globule intermediates when denatured by acid or GuHCl. In the presence of TFE, it transforms into a highly helical state. In our first study on its folding mechanism (Z Λ‡erovnik et al., Proteins 32:296-303), the kinetics measured by circular dich