The human myeloid nuclear differentiation antigen, MNDA, is expressed only in myelomonocytic and a subset of B lymphoid hematopoietic cells. MNDA is uniformly distributed throughout the interphase cell nucleus and associates with chromatin, but does not bind specific DNA sequences. We recently demon
✦ LIBER ✦
The FK506-binding protein 25 functionally associates with histone deacetylases and with transcription factor YY1
✍ Scribed by Yang, W.-M.
- Book ID
- 111748121
- Publisher
- Nature Publishing Group
- Year
- 2001
- Tongue
- English
- Weight
- 415 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0261-4189
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## Abstract Gfi‐1 and Gfi‐1B can repress transcription and play important roles in hematopoietic cell survival and differentiation. Although these proteins are known to bind DNA through a C‐terminal zinc‐finger domain and may require an N‐terminal SNAG domain (SNAIL/Gfi‐1) to repress transcription,