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The first total synthesis of novel human chymase inhibitor SPF32629A

✍ Scribed by Srinivasa Rao Vegi; Shanthaveerappa K. Boovanahalli; Arun Prakash Sharma; K. Mukkanti

Publisher: Elsevier Science
Year: 2008
Tongue: French
Weight: 167 KB
Volume: 49
Category: Article
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2008.08.048

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✦ Synopsis

The first total synthesis of SPF32629A, a novel human chymase inhibitor, has been accomplished from the readily available precursor 4-nitropyridine N-oxide, following an efficient strategy with a sequence of eight straightforward steps.

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