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The first total synthesis of nidulalin A, a dihydroxanthone possessing multiple bioactivities

โœ Scribed by Tatsuta, Kuniaki (author);Yoshihara, Shusuke (author);Hattori, Nobutaka (author);Yoshida, Shinpei (author);Hosokawa, Seijiro (author)


Book ID
109869056
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
131 KB
Volume
62
Category
Article
ISSN
0021-8820

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The first total synthesis of calbistrin
โœ Kuniaki Tatsuta; Manabu Itoh; Ryusuke Hirama; Nobuyuki Araki; Masayuki Kitagawa ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 282 KB

The octahydronaphthopyranone moiety is synthesized from methyl ~t-D-mannopyranoside through the intramolecular Diels-Alder reaction, and the tetmenedicarboxylic acid moiety is from the enzymatically prepared anti-compound. Both moieties were coupled to accomplish the total synthesis of calbistrin A