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The first synthesis of enantiomerically pure cyclopropylphosphonate analogues of nucleotides via asymmetric cyclopropanation of chiral (1-diethoxyphosphoryl)vinyl p-tolyl sulfoxide

✍ Scribed by Wanda H. Midura; Jerzy A. Krysiak; Marian Mikołajczyk


Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
397 KB
Volume
14
Category
Article
ISSN
0957-4166

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📜 SIMILAR VOLUMES


Asymmetric cyclopropanation of chiral (1
✍ Wanda H Midura; Marian Mikołajczyk 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 292 KB

E-(S)-(1-Dimethoxyphosphoryl-2-phenyl)vinyl p-tolyl sulfoxide 3 was found to undergo cyclopropanation with sulfur ylides [dimethyl(oxo)sulfonium methylide, diphenyl sulfonium isopropylide and ethyl (dimethylsulfuranylidene)acetate (EDSA)] in a highly diastereoselective manner. The major diastereomer

1,3-Dipolar cycloaddition of diazoalkane
✍ Wanda H. Midura; Jerzy A. Krysiak; Marian Mikolajczyk 📂 Article 📅 1999 🏛 Elsevier Science 🌐 French ⚖ 737 KB

Cycloaddition of diazomethane and ethyl diazoacetate to a-(diethoxyphosphoryl)vinyl p-tolyl sulfoxide la and its P-substituted analogues (Me, Ph) results in the formation of 3-phosphorylpyrazoles in high yield. The reaction of chiral (S)-(+tla with diphenyldiazomethane proceeds fYly diastereoselecti

ChemInform Abstract: 1,3-Dipolar Cycload
✍ Wanda H. Midura; Jerzy A. Krysiak; Marian Mikolajczyk 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v