The first practical asymmetric synthesis of R and S-Warfarin
β Scribed by Andrea Robinson; Hui-Yin Li; John Feaster
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- French
- Weight
- 239 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
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Abstmctz A convenient new asymmetric synthesis of both enaatiomcrs of eryrhro-3-hydroxylcuciae is desctibed. The key steps involve Sharpless asymmetric dihydroxylation (AD) of a&unsaturated ester 3, cyclic sulphate formation from the resulting diol, SNZ reaction with sodium azide, deesterification w
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