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The First Optically Active Cluster: Resolution of Enantiomers and Absolute Configuration of SFeCoMoCp(CO)8

✍ Scribed by Dipl.-Chem. Felix Richter; Prof. Dr. Heinrich Vahrenkamp


Publisher
John Wiley and Sons
Year
1980
Tongue
English
Weight
122 KB
Volume
19
Category
Article
ISSN
0044-8249

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Chiral resolution and absolute configura
✍ Ornella Azzolina; Vittorio Dal Piaz; Simona Collina; Maria Paola Giovannoni; Car πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 96 KB πŸ‘ 2 views

In a series of 5-acyl-6-phenyl-2,4-substituted-3(2H)-pyridaziones the derivative 1a, with a sulfur stereogenic center, had the most potent activity as human platelet aggregation inhibitor. The resolution of rac-1a was successfully performed by chiral chromatography on Chiralcel OD-R, OD-H, and Chira