The first, highly efficient synthesis of spacer-armed O-glycans on GlyCAM-1 and PSGL-1: the counter-receptors for L- and P-selectin

✍ Scribed by Nobumasa Otsubo; Hideharu Ishida; Makoto Kiso

• Book ID: 104210279
• Publisher: Elsevier Science
• Year: 2000
• Tongue: French
• Weight: 157 KB
• Volume: 41
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)00492-5

✦ Synopsis

A pair of spacer-armed O-glycans containing sulfated/nonsulfated sialyl Le x (sLe x ) determinant on GlyCAM-1 and PSGL-1, the counter-receptor glycoproteins for L-and P-selectin, were synthesized for the first time in a highly efficient manner employing a simultaneous glycosylation procedure.